Publication Detail

Aspects of Iron-Catalyzed Lipid Oxidation in Fish Sarcoplasmic Reticulum

2 pp.

The purpose of the work was to determine the role of ionic iron in lipid oxidation of isolated fish sarcoplasmic reticulum (SR) as a model for stored, ground fish muscle. Exogenous Fe3+ had only a minor role. Increasing concentrations of Fez+ led to a greater extent of lipid oxidation, a more rapid
maximal rate, but an increased lag time. It is suggested that the last occurs because Fe2+ functions as an antioxidant and reduces membrane antioxidant radicals to their active form. This conclusion is based on the observation that elimination of the antioxidative capacity of the membrane by storage
or prior reaction eliminates the lag phase over a range of Fez+c oncentrations and Fe2+/Fe3+ra tios. The rapid rate of Fe2+ oxidation in the presence of membrane compared to that in its absence suggests that the oxidation is driven by previously formed lipid peroxides reacting with Fez+.

type: Full theses / dissertations

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